{"id":3793,"date":"2021-07-31T22:47:28","date_gmt":"2021-07-31T14:47:28","guid":{"rendered":"https:\/\/esthersmusiccreations.com\/?p=3793"},"modified":"2021-07-31T22:47:28","modified_gmt":"2021-07-31T14:47:28","slug":"%e6%8a%97%e8%85%ab%e7%98%a4%e5%a3%9e%e6%ad%bb%e5%9b%a0%e5%ad%90%e5%8f%af%e9%99%8d%e4%bd%8eibd%e6%82%a3%e8%80%85%e7%bd%b9%e6%82%a3%e7%9b%b4%e8%85%b8%e7%99%8c","status":"publish","type":"post","link":"https:\/\/esthersmusiccreations.com\/%e6%8a%97%e8%85%ab%e7%98%a4%e5%a3%9e%e6%ad%bb%e5%9b%a0%e5%ad%90%e5%8f%af%e9%99%8d%e4%bd%8eibd%e6%82%a3%e8%80%85%e7%bd%b9%e6%82%a3%e7%9b%b4%e8%85%b8%e7%99%8c\/","title":{"rendered":"\u6297\u816b\u7624\u58de\u6b7b\u56e0\u5b50\u53ef\u964d\u4f4eIBD\u60a3\u8005\u7f79\u60a3\u76f4\u8178\u764c"},"content":{"rendered":"<p>\u4eca\u5929\u770b\u5230CCF\u5728\u81c9\u66f8\u5206\u4eab\u7684\u4e00\u7bc7\u6587\u7ae0\uff0c\u82b1\u4e86\u4e00\u9ede\u6642\u9593\u7ffb\u8b6f\uff0c\u5e0c\u671b\u53ef\u4ee5\u5e6b\u52a9IBD\u7684\u75c5\u53cb\u4e86\u89e3<\/p>\n<p>\u6b64\u6587\u7684\u6700\u5f8c\u6709\u653e\u4e0a\u539f\u51fa\u8655\u7684\u9023\u7d50\uff0c\u770b\u5f97\u61c2\u82f1\u6587\u7684\u4eba\u53ef\u4ee5\u4e0a\u53bb\u770b\u539f\u6587\u5594\uff01<\/p>\n<p>&nbsp;<\/p>\n<p class=\"p1\">\u5c0d\u65bc<span class=\"s1\">IBD<\/span>\u75c5\u60a3\u6700\u4e0d\u60f3\u807d\u5230\u5176\u4e2d\u4e4b\u4e00\u7684\u8a3a\u65b7\u5c31\u662f\u7f79\u60a3\u76f4\u8178\u764c\uff0c\u60a3\u8005\u5f97\u5230\u76f4\u8178\u764c\u7684\u6a5f\u7387\u53d6\u6c7a\u65bc\u67d0\u4e9b\u56e0\u7d20\uff0c\u5176\u4e2d\u5305\u542b\u6f70\u760d\u6027\u7d50\u8178\u708e\u548c\u514b\u9686\u6c0f\u75c7\u7684\u60a3\u8005\u3001\u75c5\u53f2\u8d85\u904e\u516b\u5e74\u4ee5\u4e0a\u6216\u662f\u66f4\u4e45\u3001\u8f03\u56b4\u91cd\u6216\u662f\u5ee3\u6cdb\u7684\u8178\u708e\u3001\u539f\u767c\u6027\u786c\u5316\u6027\u81bd\u7ba1\u708e\uff08\u4e00\u7a2e\u7f55\u898b\u7684\u75be\u75c5\uff0c\u6703\u5c0e\u81f4\u81bd\u7ba1\u708e\u75c7\u548c\u7622\u75d5\u5f62\u6210\uff09\u3001\u767c\u80b2\u4e0d\u826f\u6216\u7d30\u80de\u8b8a\u5316\uff0c\u9019\u4e9b\u7d30\u80de\u662f\u764c\u75c7\u3001\u7d50\u8178\u6216\u76f4\u8178\u7684\u524d\u9ad4\u7d30\u80de\uff0c\u6216\u6709\u7d50\u8178\u3001\u76f4\u8178\u764c\u7684\u5bb6\u65cf\u53f2\u3002\u6b64\u5916\uff0c\u9664\u4e86\u6027\u3001\u80a5\u80d6\u3001\u98f2\u9152\u548c\u5438\u7159\u53f2\u7b49\u56e0\u7d20\u5916\uff0c\u5e74\u9f61\u589e\u52a0\u4e5f\u662f\u53e6\u4e00\u500b\u5371\u96aa\u56e0\u7d20\u3002<\/p>\n<p class=\"p1\">\u5118\u7ba1\u78ba\u5207\u7684\u9014\u5f91\u5c1a\u4e0d\u6e05\u695a\uff0c\u4f46\u8178\u80c3\u9053\u7684\u6162\u6027\u767c\u708e\u53ef\u80fd\u662f<span class=\"s1\"> IBD <\/span>\u8207\u76f4\u8178\u764c\u4e4b\u9593\u7684\u95dc\u806f\u3002\u767c\u708e\u589e\u52a0\u4e86\u5065\u5eb7\u7d30\u80de\u7a81\u8b8a\u7522\u751f\u816b\u7624\u7d30\u80de\u7684\u53ef\u80fd\u6027\u3002\u4fc3\u4f7f\u767c\u708e\u7684\u56e0\u7d20\u4e4b\u4e00\u662f\u7531\u7a31\u70ba\u816b\u7624\u58de\u6b7b\u56e0\u5b50<span class=\"s1\"> \u03b1 (TNF-\u03b1) <\/span>\u7684\u57fa\u56e0\u7522\u751f\u7684\u86cb\u767d\u8cea\u3002\u800c\u300c\u6297\u816b\u7624\u58de\u6b7b\u56e0\u5b50\u300d\u7684\u85e5\u7269\uff0c\u5982<span class=\"s1\">infliximab<\/span>\u548c<span class=\"s1\">adalimumab<\/span><span class=\"s2\">\uff0c\u53ef\u4ee5\u6291\u5236\u9019\u7a2e\u86cb\u767d\u8cea\u7684\u7522\u751f\uff0c\u6e1b\u8f15\u767c\u708e\u3002<\/span><\/p>\n<p class=\"p1\">\u6216\u8a31\u807d\u8d77\u4f86\u9055\u53cd\u5e38\u7406\uff0c\u4f46\u767c\u8868\u5728\u6162\u6027\u767c\u708e\u6027\u8178\u9053\u75be\u75c5<span class=\"s1\">(IBD)<\/span>\u96dc\u8a8c\u4e0a\u7684\u4e00\u9805\u65b0\u7814\u7a76\u80cc\u5f8c\u7684\u7814\u7a76\u4eba\u54e1\u8abf\u67e5\u4e86\u6297\u816b\u7624\u58de\u6b7b\u56e0\u5b50\u548c\u5176\u4ed6\u7684\u6cbb\u7642\u85e5\u7269\uff0c\u5305\u62ec\u985e\u56fa\u9187\u3001\u514d\u75ab\u6291\u5236\u5291\u548c\u975e\u985e\u56fa\u9187\u6d88\u708e\u6b62\u75db\u85e5\uff0c\u964d\u4f4e\u4e86\u60a3\u8005\u7f79\u60a3\u76f4\u8178\u764c\u7684\u98a8\u96aa\u3002\u4ed6\u5011\u767c\u73fe\u6297\u816b\u7624\u58de\u6b7b\u56e0\u5b50\u7684\u751f\u7269\u88fd\u5291\u8b93\u6f70\u760d\u6027\u7d50\u8178\u708e\u548c\u514b\u9686\u6c0f\u75c7\u75c5\u60a3\uff0c\u7f79\u60a3\u76f4\u8178\u764c\u7684\u98a8\u96aa\u986f\u8457\u964d\u4f4e\uff0c\u9019\u70ba\u672a\u4f86\u7684\u7814\u7a76\u63d0\u4f9b\u4e86\u4e00\u689d\u9014\u5f91\uff0c\u4ee5\u53ca\u7ba1\u7406<span class=\"s1\">IBD<\/span>\u548c\u76f4\u8178\u764c\u98a8\u96aa\u7684\u6709\u6548\u7642\u6cd5\u3002<\/p>\n<p class=\"p1\">\u5177\u9ad4\u4f86\u8aaa\uff0c\u7814\u7a76\u4eba\u54e1\u767c\u73fe\u4e86\u4ee5\u4e0b\u5e7e\u9ede\uff1a<\/p>\n<p class=\"p1\"><span class=\"s1\">1. <\/span>\u514b\u9686\u6c0f\u75c7\u548c\u6f70\u760d\u6027\u7d50\u8178\u708e\u60a3\u8005\u5982\u679c\u63a5\u53d7\u4efb\u4f55\u6297\u816b\u7624\u58de\u6b7b\u56e0\u5b50\u6cbb\u7642\uff0c\u7121\u8ad6\u662f\u55ae\u7368\u4f7f\u7528\u6297<span class=\"s1\">TNF<\/span>\u85e5\u7269\u9084\u662f\u8207\u514d\u75ab\u6291\u5236\u5291\u5408\u4f75\u4f7f\u7528\uff0c\u90fd\u4e0d\u592a\u53ef\u80fd\u88ab\u8a3a\u65b7\u70ba\u76f4\u8178\u764c\u3002<\/p>\n<p class=\"p1\"><span class=\"s1\">2. <\/span>\u8207\u6f70\u760d\u6027\u5927\u8178\u708e\u60a3\u8005\u76f8\u6bd4\uff0c\u6297<span class=\"s1\">TNF<\/span>\u85e5\u7269\u66f4\u80fd\u964d\u4f4e\u514b\u9686\u6c0f\u75c7\u60a3\u8005\u88ab\u8a3a\u65b7\u70ba\u7d50\u76f4\u8178\u764c\u7684\u6a5f\u7387\u3002<\/p>\n<p class=\"p3\">3. <span class=\"s2\">\u8207\u6297<\/span>TNF<span class=\"s2\">\u76f8\u6bd4\uff0c\u5305\u62ec<\/span>vedolizumab, ustekinumab, natalizumab, and tofacitinib, <span class=\"s2\">\u5728\u5167\u7684\u5176\u4ed6\u85e5\u7269\u7684\u6578\u64da\u8f03\u5c11\uff0c\u6211\u5011\u9700\u8981\u7b49\u5f85\u66f4\u591a\u6578\u64da\uff0c\u770b\u770b\u9019\u4e9b\u85e5\u7269\u662f\u5426\u4e5f\u80fd\u770b\u5230\u540c\u6a23\u7684\u7642\u6548\uff1f<\/span><\/p>\n<p class=\"p1\"><span class=\"s1\">4. <\/span>\u55ae\u7368\u4f7f\u7528\u985e\u56fa\u9187\u548c\u514d\u75ab\u8abf\u7bc0\u5291\u4e26\u6c92\u6709\u986f\u8457\u6539\u8b8a\u514b\u9686\u6c0f\u75c7\u60a3\u8005\u5f97\u5230\u76f4\u8178\u764c\u7684\u6a5f\u7387\u3002\u7136\u800c\uff0c\u9019\u4e9b\u6cbb\u7642\u537b\u63d0\u9ad8\u4e86\u6f70\u760d\u6027\u7d50\u8178\u708e\u60a3\u8005\u7684\u6a5f\u7387\u3002<\/p>\n<p class=\"p1\"><span class=\"s1\">5. 5-ASA <\/span>\u662f\u4e00\u7a2e\u975e\u985e\u56fa\u9187\u6d88\u708e\u6b62\u75db\u85e5\uff0c\u540c\u6a23\u53ef\u4ee5\u964d\u4f4e\u514b\u9686\u6c0f\u75c7\u548c\u6f70\u760d\u6027\u5927\u8178\u708e\u60a3\u8005\u88ab\u8a3a\u65b7\u70ba\u76f4\u8178\u764c\u7684\u6a5f\u7387\u3002<\/p>\n<p class=\"p1\">\u9019\u5c0d\u60a3\u8005\u610f\u5473\u8457\u4ec0\u9ebc\uff1f<\/p>\n<p class=\"p1\">\u9019\u4e9b\u7d50\u679c\u8868\u660e\uff0c\u6cbb\u7642<span class=\"s1\"><i> IBD <\/i><\/span>\u6839\u6e90\u7684\u6f5b\u5728\u708e\u75c7\u7684\u7642\u6cd5\u4e5f\u53ef\u80fd\u964d\u4f4e\u60a3\u8005\u60a3\u76f4\u8178\u764c\u7684\u98a8\u96aa\u3002\u7814\u7a76\u4eba\u54e1\u5728\u7814\u7a76\u4e2d\u6307\u51fa\u300c\u9019\u4e9b\u7d50\u679c\u4ee4\u4eba\u653e\u5fc3\uff0c\u6297<span class=\"s1\"> TNFs \u85e5\u7269<\/span>\u4f3c\u4e4e\u8207<span class=\"s1\"> IBD \u964d\u4f4e<\/span>\u76f4\u8178\u764c\u7684\u98a8\u96aa\u6709\u95dc\u3002\u300d<\/p>\n<p class=\"p1\">\u5118\u7ba1\u5982\u6b64\uff0c\u9019\u9805\u7814\u7a76\u9084\u662f\u4f7f\u7528\u56de\u6eaf\u6027\u6578\u64da\u78ba\u5b9a\u4e86\u9019\u500b\u95dc\u806f\uff0c\u672a\u4f86\u7684\u7814\u7a76\u5c07\u5e0c\u671b\u901a\u904e\u524d\u77bb\u6027\u6216\u672a\u4f86\u7684\u968a\u5217\u7814\u7a76\u4f86\u78ba\u8a8d\u9019\u500b\u76f8\u95dc\u6027\u3002\u6b64\u5916\uff0c\u6297<span class=\"s1\">TNF<\/span>\u85e5\u7269\u662f<span class=\"s1\">IBD<\/span>\u6cbb\u7642\u65b9\u6848\u4e2d\u7684\u4e00\u7a2e\uff1a\u53ef\u80fd\u6703\u6216\u53ef\u80fd\u4e0d\u6703\u6839\u64da\u7279\u5b9a\u60a3\u8005\u7684\u75be\u75c5\u56b4\u91cd\u7a0b\u5ea6\u7b49\u56e0\u7d20\u958b\u8655\u65b9\u3002<\/p>\n<p class=\"p1\">\u5982\u4f55\u964d\u4f4e\u7f79\u60a3\u76f4\u8178\u764c\u7684\u98a8\u96aa<\/p>\n<p class=\"p1\">\u5118\u7ba1\u5927\u591a\u6578\u514b\u9686\u6c0f\u75c7\u548c\u6f70\u760d\u6027\u7d50\u8178\u708e\u60a3\u8005\u6bd4\u8f03\u4e0d\u6703\u60a3\u4e0a\u76f4\u8178\u764c\uff0c\u4f46\u8207\u60a8\u7684\u91ab\u751f\u8a0e\u8ad6\u98a8\u96aa\u662f\u5f88\u91cd\u8981\u7684\u4e8b\u60c5\u3002\u76f4\u8178\u764c\u5728\u65e9\u671f\u767c\u73fe\u7684\u6cbb\u7652\u7387\u5f88\u9ad8\u3002\u9019\u88e1\u6709\u4e00\u4e9b\u65b9\u6cd5\u53ef\u4ee5\u5e6b\u52a9\u60a8\u5927\u5927\u964d\u4f4e\u7f79\u60a3\u76f4\u8178\u764c\u7684\u98a8\u96aa\uff1a<\/p>\n<p class=\"p1\">\u6bcf\u5e74\u81f3\u5c11\u770b\u4e00\u6b21\u60a8\u7684\u8178\u80c3\u79d1\u91ab\u751f<\/p>\n<p class=\"p1\">\u5217\u51fa\u60a8\u9047\u5230\u7684\u4efb\u4f55\u65b0\u7684\u6216\u76f8\u95dc\u7684\u75c7\u72c0\uff0c\u4ee5\u4fbf\u8207\u60a8\u7684\u91ab\u751f\u8a0e\u8ad6<\/p>\n<p class=\"p1\">\u6309\u898f\u5b9a\u670d\u85e5\u4ee5\u63a7\u5236\u75c7\u72c0<\/p>\n<p class=\"p1\">\u5373\u4f7f\u89ba\u5f97\u72c0\u6cc1\u4e0d\u932f\u4e5f\u4e0d\u8981\u96a8\u610f\u505c\u85e5<\/p>\n<p>&nbsp;<\/p>\n<p>\u539f\u6587\u9023\u7d50\uff1ahttps:\/\/www.crohnscolitisfoundation.org\/blog\/anti-tnf-therapy-could-lower-colorectal-cancer-risk-ibd-patients<\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u4eca\u5929\u770b\u5230CCF\u5728\u81c9\u66f8\u5206\u4eab\u7684\u4e00\u7bc7\u6587\u7ae0\uff0c\u82b1\u4e86\u4e00\u9ede\u6642\u9593\u7ffb\u8b6f\uff0c\u5e0c\u671b\u53ef\u4ee5\u5e6b\u52a9IB [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":3172,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_jetpack_memberships_contains_paid_content":false,"footnotes":""},"categories":[3,16],"tags":[],"jetpack_sharing_enabled":true,"jetpack_featured_media_url":"https:\/\/esthersmusiccreations.com\/wp-content\/uploads\/2021\/03\/610B0035-B472-4441-A4C1-70090291C0B6_1_105_c.jpeg","_links":{"self":[{"href":"https:\/\/esthersmusiccreations.com\/wp-json\/wp\/v2\/posts\/3793"}],"collection":[{"href":"https:\/\/esthersmusiccreations.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/esthersmusiccreations.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/esthersmusiccreations.com\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/esthersmusiccreations.com\/wp-json\/wp\/v2\/comments?post=3793"}],"version-history":[{"count":2,"href":"https:\/\/esthersmusiccreations.com\/wp-json\/wp\/v2\/posts\/3793\/revisions"}],"predecessor-version":[{"id":3797,"href":"https:\/\/esthersmusiccreations.com\/wp-json\/wp\/v2\/posts\/3793\/revisions\/3797"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/esthersmusiccreations.com\/wp-json\/wp\/v2\/media\/3172"}],"wp:attachment":[{"href":"https:\/\/esthersmusiccreations.com\/wp-json\/wp\/v2\/media?parent=3793"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/esthersmusiccreations.com\/wp-json\/wp\/v2\/categories?post=3793"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/esthersmusiccreations.com\/wp-json\/wp\/v2\/tags?post=3793"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}